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Visualization of carboxylesterase 2 with a near-infrared two-photon fluorescent probe and potential evaluation of its anticancer drug effects in an orthotopic colon carcinoma mice model
发布时间:2020-04-23 发布者: 浏览次数:

Chemical Communications, 2020, 56, 4412 - 4415 Full text

Yan Wang, Feifei Yu, Xianzhu Luo, Mingshun Li, Linlu Zhao* and Fabiao Yu*

https://pubs.rsc.org/en/content/articlelanding/2020/cc/d0cc00297f/


Abstract

We establish a near-infrared two-photon fluorescent probe for the detection of CE2 with high selectivity and sensitivity. This probe exhibits low cytotoxicity and superior tissue penetration ability for evaluating the real-time activity of CE2 in living cells, in cancer tissues, and in a colon carcinoma mice model.


海南省生物材料与医疗器械工程研究中心/海南省创伤与灾难救援研究重点实验室版权所有 ©2024

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