刘异凡简历
姓名：刘异凡
邮箱： lyf_0318@sina.com
个人网页：https://pharmacy.hebmu.edu.cn/a/2021/07/10/6880A0A61A564A29B6A7C66662079060.html
教育工作经历：
河北医科大学药学院，副教授
博士/硕士招生方向
药学
研究领域：
可用于肿瘤诊断和治疗的双效小分子化合物的设计、合成及应用
学术成果：
一、期刊论文
1.A tyrosinase-activated Pt(II) complex for melanoma photodynamic therapy and ffuorescence imaging. Sensor Actuat B- Chem. 2023; 374; 132836. (中科院一区，IF：9.221)
2.Energy-Level Control via Molecular Planarization and Its Effect on Interfacial Charge-Transfer Processes in Dye-Sensitized Solar Cells. J Phys. Chem. C. 2019; 123; 13531-13537. (JCR Q2, IF:4.309)
3.Rhodamine derivatives bearing thiourea groups serve as fluorescent probes for selective detection of ATP in mitochondria and lysosomes. Sensor Actuat B- Chem. 2019; 281: 350-358. (JCR Q1, IF:6.393)
4.A new kind of rhodamine-based fluorescence turn-on probe for monitoring ATP in mitochondria. Sensor Actuat B- Chem. 2018; 265: 429-434. (JCR Q1, IF:6.393)
5.Fluoride ion activated CO2 sensing using sol-gel system. Dyes and Pigments. 2017; 139: 658-663. (JCR Q2, IF:4.018)
6.Fluorescent and colorimetric chemosensors for anions, metal ions, reactive oxygen species, biothiols, and gases. B KOREAN CHEM SOC. 2016; 37: 1661-1678. (IF:0.60)
7.Pyrene based fluorescent probes for detecting endogenous zinc ions in the cells. Dyes and Pigments. 2015; 113: 372-377. (JCR Q2, IF:4.018)
8.A bispyrene derivative as a selective fluorescent probe for RNA. Chem. Comm. 2014; 50: 2505-2507. (JCR Q1, IF:6.164)
9.New iridium complexes with two pre-organized urea groups and thiourea groups as phosphorescent chemosensors for H2PO4- and chiral carboxylates. Dyes and Pigments. 2014; 100: 241-246. (JCR Q2, IF:4.018)
10.A new phosphorescent chemosensor bearing Zn-DPA sites for H2PO4-. Dyes and Pigments. 2014; 106: 20-24. (JCR Q2, IF: 4.018)
11.Visible light-harvesting perylenebisimide-fullerene (C60) dyads with bidirectional “ping-pong” energy transfer as triplet photosensitizers for photooxidation of 1,5-dihydroxynaphthalene. Chem. Comm. 2012; 48: 3751-3753. (JCR Q1, IF: 6.164)
12.BF2-bound chromophore-containing N^N Pt(II) bisacetylide complex and its application as sensitizer for triplet-triplet annihilation based upconversion. RSC Advances. 2012; 2: 1061-1067. (JCR Q2, IF:3.049)
13.Ratiometric luminescent molecular oxygen sensors based on uni-luminophores of C^N Pt(II)(acac) complexes that show intense visible-light absorption and balanced fluorescence/ phosphorescence dual emission. Chem. Comm. 2011; 47: 11471-11473. (JCR Q1, IF: 6.164)
14.Accessing the long-lived near-IR-emissive triplet excited state in naphthalenediimide with light-harvesting diimide platinum(II) bisacetylide complex and its application for upconversion. Dalton Trans. 2011; 40: 9085-9089. (JCR Q2, IF:4.052)
15.Enantioselective recognition of tartaric acids with ethynylated carbazole-based chiral bisboronic acid chemosensors with improved response at acidic pH. J. Fluoresc. 2011; 21: 1979-1986. (JCR Q3, IF:1.913)
二、科研项目
1、具有识别酪氨酸酶功效的BODIPY-TEMPO类光敏剂的设计合成及其细胞成像和光动力性质研究，CYYQ201902，河北医科大学春雨计划优秀青年项目，30万
2、基于荧光共聚焦成像和光动力治疗的黑色素瘤诊断治疗剂的研究，BJ2021051，河北省教育厅拔尖人才项目，10万
3、基于酪氨酸酶识别机制的恶性黑色素瘤荧光示踪和光动力治疗的双效诊疗药物研究，H2020206613，河北省自然科学基金医药联合项目，10万
4、以BODIPY为基础的可用于检测和杀伤黑色素瘤细胞的新型抗癌药的基础研究，C20190351，河北省人社厅资助留学人员项目，3万
