彭雅南，副研究员
联系方式：pengyanan2022@muhn.edu.cn
教育及工作经历：
2025-至今 海南医科大学 衰老与肿瘤国际研究中心 PI
2023-2025 海南大学 材料科学与工程学院 博士后
2020-2023 海南医学院 博士（临床检验诊断学）
2017-2020 海南医学院 基础医学与生命科学学院 教辅
2014-2017 海南医学院 硕士（神经病学）
2008-2013 海南医学院 学士（临床医学）
研究方向：
DNA纳米技术在衰老与肿瘤疾病的诊疗应用研究：
l 新型DNA纳米结构的设计和构建；
l 基于DNA纳米技术在衰老与肿瘤相关的体外检测、细胞成像和药物递送策略；
l DNA纳米技术服务于衰老与肿瘤相关医学机制研究的纳米工具开发。
近年主持的研究项目：
[1] 2026.01-2028.12，国家自然科学基金青年科学基金项目（C类）《DNA tile可逆标记系统实时读取单细胞glycoRNA时空动态信息的研究》，项目编号：82502800，30万，主持；
[2] 2025.03-2026.03，海南省自然科学基金青年项目《适体开关定点编程的DNA tile纳米平台在临床体液样本中ATP的信号放大检测》，项目编号：825QN287，6万，主持；
[3] 2024.12-2025.12，海南省博士后研究项目《血糖自驱动的磁性微马达功能化DNA纳米阵列对循环肿瘤细胞的主动诱捕、精准富集新策略》，15万，主持。
代表性论文：
[1] Yanan Peng (#), Qiumei Pu (#), Liangqing Lu, Qionglin Zhou, Xinxin Xiao, Xiangde Lai, Xuan Zhao, Bin Qiao, Qiang Wu (*). Erasable Fluorescence Imaging Technology Enables Continuous Tracking for Identical Living Cells. Angewandte Chemie International Edition, 2025, e202503818. (IF: 16.9，中科院1区)
[2] Yanan Peng (#), Zhijun Gao (#), Bin Qiao, Dongxia Li, Huajie Pang, Xiangde Lai, Qiumei Pu, Rui Zhang, Xuan Zhao, Guangyuan Zhao, Dan Xu, Yuanyuan Wang, Yuxiang Ji, Hua Pei, Qiang Wu (*). Size-controlled DNA tile self-assembly nanostructures through caveolae-mediated endocytosis for signal-amplified imaging of microRNAs in living cells. Advanced Science, 2023, 2300614. (IF: 14.3，中科院1区)
[3] Qiumei Pu (#), Liangqing Lu (#), Yanghong Zhao (#), Dongxia Li, Mengli Yao, Qionglin Zhou, Xinxin Xiao, Yuzhong Jia, Xuan Zhao, Xiangde Lai, Qian Chen, Yuxiang Ji, Bin Qiao, Hua Pei (*), Yanan Peng (*), Qiang Wu (*). Self-Propelled Magnetic Micromotor-Functionalized DNA Tile System for Autonomous Capture of Circulating Tumor Cells in Clinical Diagnostics. Advanced Science, 2025, e08636. (IF: 14.1，中科院1区)
[4] Liangqing Lu, Zhijun Gao, Yanghong Zhao, Qiumei Pu, Mingxin Jian, Bin Qiao, Qiang Wu, Ping Zhou, and Yanan Peng (*). A DNA-Tile-Based Fluorescence Lighting System for Signal-Amplified Imaging at the Single Live-Cell Level. Analytical Chemistry, 2025, 97, 47, 26045–26053. (IF: 6.7，中科院1区)
[5] Yanan Peng (#), Huajie Pang (#), Zhijun Gao, Dongxia Li, Xiangde Lai, Delun Chen, Rui Zhang, Xuan Zhao, Xinping Chen, Hua Pei, Jinchun Tu, Bin Qiao (*), Qiang Wu (*). Kinetics-accelerated one-step detection of MicroRNA through spatially localized reactions based on DNA tile self-assembly. Biosensors and Bioelectronics, 2023, 222: 114932. (IF: 10.7，中科院1区)
[6] Yanan Peng (#), Dongxia Li (#), Zhijun Gao, Qiumei Pu, Huajie Pang, Xiangde Lai, Rui Zhang, Xuan Zhao, Guangyuan Zhao, Dan Xu, Feng Han, Yuanyuan Wang, Yuxiang Ji, Hua Pei, Qiang Wu (*). Protonation-mediated DNA tile self-assembly with nuclease resistance characteristic for signal-amplified detection of microRNAs. Biosensors and Bioelectronics, 2024, 246: 115869. (IF: 10.5，中科院1区)
[7] Dongxia Li (#), Yanan Peng (#) (*), Liangqing Lu (#), Delun Chen, Bingrong Wang, Qiumei Pu, Qionglin Zhou, Xinxin Xiao, Mingpeng Fu, Xiaohong Wang, Jinchun Tu (*), Hua Pei (*), Qiang Wu (*). Programmed DNA tile response system enabled accurate detection of ATP for clinical diagnosis. Chemical Engineering Journal, 2024, 499: 156270. (IF: 13.2，中科院1区)
[8] Zhijun Gao (#), Qiumei Pu (#), Dongxia Li, Rui Zhang, Xiangde Lai, Xuan Zhao, Bin Qiao, Hua Pei, Yanan Peng (*), Hua Wang (*), Qiang Wu (*). One-Step Strand Displacement-Mediated Nucleic Acids Signal-Amplified Analytical Strategy based on Superparamagnetism-Functionalized DNA Arrays. International Journal of Biological Macromolecules. 2025, 308: 142596. (IF: 8.5，中科院2区)
[9] Huajie Pang (#), Yanan Peng (#), Rui Zhang, Zhijun Gao, Xiangde Lai, Dongxia Li, Xuan Zhao, Yuanyuan Wang, Hua Pei, Bin Qiao (*), Yuxiang Ji (*), Qiang Wu (*). A triggered DNA nanomachine with enzymefree for the rapid detection of telomerase activity in a one-step method, Analytica Chimica Acta. 2024, 1299: 342420. (IF: 6.0，中科院2区)
[10] Qiumei Pu (#), Xiangde Lai (#), Yanan Peng (*), Qiang Wu (*). A controllable DNA: structural features and advanced applications of i-motif. Analyst, 2025, 150, 1726-1740. (IF: 3.6，中科院3区)
注：(#)为第一作者，(*)为通讯作者。
