杨国静(PhD)教授,博士生导师
热带医学院副院长
个人简介
杨国静,女,海南医学院热带医学院副院长,研究员, 博士生导师。Acta Tropica杂志主编,爱丁堡大学荣誉研究员,海南省“千人专项”人才,校级重点学科带头人,省级重点学科方向带头人。长期从事热带病流行病学的研究工作,在传染病的时空动力学模型、数据挖掘、机器学习、分布式优化和控制方法等方向也都积累了丰富的研究经验。所掌握的现代信息学技术(包括地理信息系统、遥感分析技术、空间统计模型等)及传染病传播动力学领域均处于国内外前沿地位,围绕 “宿主与病原生态学和环境的研究”,以病原体与宿主间相互关系这一关健科学问题,从个体与群体、寄生虫与宿主、寄生虫与环境相互关系等方面,多层次、多维度地对寄生虫病传播参数、寄生虫病流行与分布预测指标进行了理论探索与技术研究。
教育经历
瑞士热带病与公共卫生研究所,巴塞尔大学 |
流行病学与公共卫生 |
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2003-2006 |
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江苏省血吸虫病防治研究所 |
病原生物学 |
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1998-2001 |
同济医科大学 |
公共卫生预防专业 |
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1991-1996 |
工作经历
海南医学院,研究员,热带医学院 |
01.2022- |
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海南医学院,研究员,公共卫生学院 |
11.2020- 01.2022 |
Senior research collaborator, Malaria modeling, Infectious Diseases Modelling unit, Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute |
07.2017- 11.2020 |
Research collaborator, Bayesian Modeling and Analysis , Bio-statistic unit, Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute |
04.2015- 04.2017 |
信息中心副主任, 江苏省寄生虫病防治研究所 |
08.2013- 03.2015 |
Research Assistant professor, Epidemiological division, Data analysis, Modeling. School of Public Health and Primary Care, The Chinese University of Hong Kong |
09.2011-08.2013 |
血吸虫病室副主任,江苏省寄生虫病防治研究所 |
08.2008 - 08.2011 |
Research fellow, School for Environmental Research, Charles Darwin University & University of Adelaide, Australia |
09.2006 - 07.2008 |
血吸虫病室,江苏省寄生虫病防治研究所 |
08.1996-08.1998; 06.2001 -02.2003 |
科研成果及荣誉
课题主要负责人(PI)主持项目:(英文为国际项目)
1. 中国疟疾消除阶段监测相应措施的优化机制研究, 国家自然科学基金面上项目(81573261),2016.1-2019.12.
2.Innovative Strategies for Sustainable Control of Asian Schistosomiasis and Other HelminthZoonoses through Socio-Ecosystem-Based Interventions, Awarded in 2011-2014 and renewed for second round in 2015-2019 by International Development Research Center (IDRC, Canada). (105509-00001002-024)
3.日本血吸虫病传播阻断阈值的研究,江苏医学重点人才(RC201198),2011-2015
4. 日本血吸虫病传播阻断特征指标及应用的研究, 国家自然科学基金,青年项目(20150226),2011-2014.
5. Development of optimal approaches to control Oncomelaniahupensisby considering intrinsic and extrinsic drivers. Awarded in 2008-2011 by UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR) (A70530).
6. Impact of predicted climate change and planned water transfer schemes on the transmission of Schistosoma japonicum in China. Awarded in 2003-2006 by UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR)(A10775).
7. Application of geographic information systems on the transmission of malaria and schistosomiasis in Jiangsu Province, China. Awarded in 1998-2001 by UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR).
8. 我国间日疟传播动力学模型构建及历史干预措施优化复现,2020海南医学院热带转化医学教育部重点实验室开放课题,5万,2021.1-2022.12 (5人)
9. 基于机器学习与疾病传播机制耦联模型优化登革热干预措施组合的研究,2021.4-2023.12,海南省自然科学基金创新团队项目,30万(8人)。
10. “全健康”研究中心,2021海南省重点新型智库(海南省首批七大重点智库之一)
主要参与人项目:
1. 重要寄生虫病诊断与监测关键技术研究,中华人民共和国卫生部,56人,2460万,2008-2011.12
2.重要寄生虫病监测关键技术研究.中华人民共和国卫生部,80人,2561.13万,2012-2016
3.重要传染病环境相关因素流行病学模型的建立:国家自然科学基金重大项目,2005.05-2010.04,140万。
4. Developing a modelling framework for malaria transmission prevention tools, Bill and Melinda Gates Foundation, OPP1170505. 2017-2019.
5. Phase 1 of Modeling support for BMGF Malaria Portfolio Analysis, Bill and Melinda Gates Foundation, OPP1207269. 2017-2019 (10万美金).
科技成果奖项:
部省级:
周晓农,洪青标,孙乐平,杨国静,杨坤,梁幼生,黄轶昕,杭德荣,2005中华预防医学会科技三等奖,《全球气候变暖对中国血吸虫病传播影响的研究》;
胡晓抒, 周晓农, 杨国静, 孙乐平, 孙宁生, 武鸣, 洪青标, 汪旸, 杨坤,2010江苏省科学技术二等奖,《公共卫生地理信息系统的构建与应用研究》
杨坤,杨国静,孙乐平,江苏省卫生厅医学新技术引进奖,一等奖,《Google earth与网络地理信息系统在血吸虫病监测预警中的作用》
杨国静 周晓农孙乐平洪青标杨坤梁幼生王伟明高扬高琪,2011江苏医学科技一等奖,《基于时空模型的血吸虫病和疟疾分布与传播规律的研究》;
杨国静、周晓农、孙乐平、洪青标、 杨 坤、梁幼生、王伟明、高 扬、高 琪,2011中华预防医学二等奖,《基于时空模型的血吸虫病和疟疾分布与传播规律的研究 》;
梁幼生,戴建荣,杨国静,孙乐平,汪伟,洪青标,神学慧,吴荣凤,周云,2014江苏省科学技术奖,二等奖,《大型水利工程与气候变化对血吸虫病传播影响的研究》;
杨坤,周晓农,杨国静,王显红,陈朝,孙乐平,梁幼生,洪青标,2014江苏医学科技奖,二等奖,《现代信息技术在血吸虫病监测与预警中的应用研究》;
周晓农,杨国静,李石柱,杨坤,许静,孙乐平,梁幼生,贾铁武,洪青标,曹淳力,2015中华医学科技奖,二等奖,《我国血吸虫病监测预警体系的建立与应用》;
周晓农、杨国静、李石柱、杨 坤、许 静、孙乐平、梁幼生、贾铁武、洪青标、曹淳力,2015中华预防医学会科技三等奖《我国血吸虫病监测预警体系的建立与应用》;
周晓农、杨国静、李石柱、杨 坤、许 静、孙乐平、梁幼生、贾铁武、洪青标、曹淳力,2016华夏医学科技二等奖《我国血吸虫病监测预警体系的建立与应用》;
孙乐平,周晓农,洪青标,杨国静,贾铁武,梁幼生,高扬,2016江苏省科学技术三等奖《江滩地区血吸虫病传播阻断关键技术创新与集成示范》
高 扬,孙乐平,马玉才,朱道建,杨国静,左引萍,洪青标,杜广林,王福彪,2016年江苏省预防医学一等奖,《扬州市血吸虫病传播阻断关键技术研究与应用》;
市级:
杨国静,孙乐平,杨坤,洪青标,梁幼生,王伟明,高琪,2011无锡市科技进步一等奖《基于时空模型的血吸虫病和疟疾分布与传播规律的研究》;
梁幼生,戴建荣,杨国静,孙乐平,汪伟,2013无锡市科技进步三等奖《大型水利工程与气候变化对血吸虫病传播影响的研究》;
孙乐平,周晓农,洪青标,杨国静,贾铁武,梁幼生,高扬,马玉才,刘瑞华,2016无锡市科技进步一等奖《江滩地区血吸虫病传播阻断关键技术创新与集成示范》
专利:
1. 吴锋,杨国静,杨坤,2013年03月20日,一种用于现场繁殖纯种钉螺的饲养笼。专利号:ZL201220518496.8. 中华人民共和国国家知识产权局。证书号:2780844。
2. 吴锋,孙乐平,杨国静,王学东,陈前,一种现场筛钉螺螺筛。专利号:ZL201320743883.6。2014年5月14日。中华人民共和国国家知识产权局。证书号:3568190
荣誉称号:
江苏省有突出贡献中青年专家, 2012
江苏省第四期“江苏省333高层次人才培养工程”第三层培养对象,2011-2015
江苏省“六大人才高峰”培养对象,2008
英文文章(仅列第一及通讯作者)
Journal Publications (*corresponding author)
Yang GJ*; Le-Yuan Shang; Xiao-Nong Zhou; Tamsin E. Lee; Bo Bi; Michael White; Thomas A. Smith; Melissa A. Penny. The empirical support for the radical treatment strategy for eliminating Plasmodium vivax in China. BMC Medicine (2021, 12.15, Accepted)
Zheng JX, Shi BY, Xia Shang, Yang GJ*, Zhou XN*. Spatial patterns of Plasmodium vivax transmission explored by multivariate auto-regressive state-space modelling: A case study in Baoshan Prefecture in southern China. Geospatial health,2021, 16(1). doi: 10.4081/gh.2021.879.
Wan H, Cui JA, Yang GJ*.Risk estimation and prediction by modeling thetransmission of the novel coronavirus (COVID-19)in mainland China excluding Hubei province. Infectious Diseases of Poverty, 9,116. 2020.
Yang GJ*, Liu Y, Shang LY, Zahng HW, Zhou XN, Penny AP, Smith AT. From Plasmodium vivax outbreak to elimination: lessons learnt from a retrospective analysis of data from Guantang. Malaria Journal, 2020.19(1):427
Yang GJ* and R. Bergquist (2018).Potential Impact of Climate Change on Schistosomiasis: A Global Assessment Attempt. Trop. Med. Infect. Dis. 2018, 3, 117.
Feng Y, T Furst, Liu L,Yang GJ*.Estimation of disability weight for paragonimiasis: a systematic analysis. . Infectious Diseases of Poverty, 2018, 7.
Shi BY*, Zheng JX, Qiu Hongjun, Yang GJ*, Xia Shang, Zhou XN. Risk assessment of malaria transmission at the border area of China and Myanmar. Infectious Diseases of Poverty, 2017, 6.
Feng Y, Liu L, Xia S, Xu JF, Bergquist R, Yang GJ* (2016) Reaching the surveillance-response stage of schistosomiasis control in the people's Republic of China: a modelling approach. Adv Parasitol , -. DOI: 10.1016/bs.apar.2016.02.006
Yang GJ, Utzinger J, Zhou XN (20130729). Interplay between environment, agriculture and infectious diseases of poverty: case studies in China. Acta Tropic,141:399-406.
Liu L, Yang GJ*, Zhu HR, Yang Kun, Ai Lin. Knowledge of, attitudes towards, and practice relating to schistosomiasis in two subtypes of a mountainous region of the People’s Republic of China. Infectious Diseases of Poverty, 2014; 3: 16
Yang GJ,Griffiths S, Utzinger J, Tanner M, Bergquist R, Utzinger J, Zhou XN (2014). China’s sustained drive to eliminate neglected tropical diseases: a review. Lancet Infectious Diseases(IF: 27.516), 14:881-892.
Yang GJ, Tanner M, Utzinger J, Malone JB, Bergquist R, Chan EY, Gao Q, Zhou XN: Malaria surveillance-response strategies in different transmission zones of the People's Republic of China: preparing for climate change. Malaria journal 2012, 11(1):426.
Yang GJ, Sun LP, Hong QB, Zhu HR, Yang K, Gao Q, Zhou XN: Optimizing molluscicide treatment strategies in different control stages of schistosomiasis in the People's Republic of China. Parasit Vectors 2012, 5(1):260.
Yang GJ, Zhou XN, Sun LP, Wu F, Zhong B, Qiu DC, Utzinger J, Bradshaw CJ: Compensatory density feedback of Oncomelaniahupensis populations in two different environmental settings in China. Parasit Vectors 2011, 4:133.
Sun LP, Liang YS, Wu HH, Tian ZX, Dai JR, Yang K, Hong QB, Zhou XN, Yang GJ*. A Google Earth-based surveillance system for schistosomiasis japonica implemented in the lower reaches of the Yangtze River, China. Parasit Vectors2011, 4: 223.
Yang GJ, Li Wei, Sun LP, Wu F, Yang K, Huang XX, Zhou XN (2010). Molluscicidal efficacies of different formulations of niclosamide: a result from Meta analysis in Chinese literatures. Parasities& Vectors 2010, 3:84doi:10.1186/1756-3305-3-84.
Yang GJ, Bergquist R, Utzinger J, Vounatsou P, Li Wei, Zhou XN (2010), The Regional Network for Asian Schistosomiasis and Other Helminth Zoonoses (RNAS+) target diseases in face of climate change. Adv Parasitol, 73: 101-35
Yang GJ, Gao Q, Zhou SS,.Malone JB, McCarroll JC, Tanner M, Vounatsou P, Bergquist R. Utzinge J, Zhou XN (2010) Future of malaria transmission in the People’s Republic of China predicted by integrated biology-driven and statistical models. Geospatial Health,5, 11-22.
Yang GJ, Bradshaw CJA, Brook BW (2009) Predicting the timing and magnitude of tropical mosquito population peaks for maximizing control efficiency, PLoSNegl Trop Dis, 3 (2): e385.
Yang GJ, Bradshaw CJA, Whelan PI, Brook BW (2008) Importance of endogenous feedback controlling the long-term abundance of tropical mosquito species. Population Ecology. 50 (3): 293-305. DOI: 10.1007/s10144-008-0082-8.
Yang GJ, Brook BW, Whelan PI, Cleland S, Bradshaw CJ (2008) Interplay between endogenous and exogenous factors in controlling temporal abundance patterns of tropical disease-carrying mosquitoes. Ecological Applications
Yang, G.J., Utzinger J., Sun, L.P., Hong, Q.B., Vounatsou, P., Tanner, M., Zhou, X.N. 2006 Effect of temperature on the development of Schistosoma japonicum within Oncomelaniahupensis, and hibernation of O. hupensis. Parasitol res. 100(4): 695-700.
Yang, G.J., Gemperli, A., Vounatsou, P., Tanner, M., Zhou, X.N., Utzinger, J. 2006. A growing degree-days based time-series analysis for prediction of Schistosoma japonicum transmission in Jiangsu province, China. Am. J. Trop. Hyg. 75(3): 549-555.
Yang, G.J.,Vounatsou, P., Tanner, M., Zhou, X.N., Utzinger J. 2006 Remote sensing for predicting potential habitats of Oncomelaniahupensis in Hongze, Baima and Gaoyou lakes in Jiangsu province, China. Geospatial Health 1: 85-92.
Yang, G.J.,Vounatsou, P., Zhou, X.N., Utzinger, J., Tanner, M., 2005. Spatio-temporal modeling of county level Schistosoma japonicum prevalence data in Jiangsu province, China, employing remotely sensed climatic data. Int. J. Parasitol. 35:155-162.
Yang, G.J.,Vounatsou, P., Zhou, X.N., Tanner, M., Utzinger, J. 2005. Effect of climate change and water resource development on the transmission of Schistosoma japonicum in China. Parassitologia 47, 127-134.
Yang, G.J.,Vounatsou, P., Zhou, X.N., Utzinger, J., Tanner, M., 2005. A review of geographic information system and remote sensing with applications to the epidemiology and control of schistosomiasis in China. Acta Trop.96: 117-129.
书籍出版:
《空间流行病学》,科学出版社,2008年1月,副主编
《血吸虫病及血吸虫病防治的社会学—导论与文献评析》,2010,主译
《流行病学》第6版,人民卫生出版社,2007年,参编
《实用钉螺学》,科学出版社,2005年,参编