(一)个人基本情况
李冬洋,女,汉族,中共党员,出生于1991年3月,黑龙江省大庆市人,生理学专业博士,讲师,研究领域为下丘脑神经内分泌,现就职于生理学教研室。
(二)教育背景
2010年9月至2015年6月,就读于齐齐哈尔医学院临床专业,获学士学位;
2015年9月至2020年6月,就读于哈尔滨医科大学生理学专业(硕博连读),获博士学位。
(三)所获荣誉
1、青年教师教学大赛三等奖,院级,2021年。
2、指导学生参加第二届基础医学与创新论坛暨实验设计大赛一等奖,省部级,2021年。
3、指导学生参加第二届基础医学与创新论坛暨实验设计大赛三等奖,国家级,2021年。
4、指导学生参加第六届国际生理学知识竞赛一等奖, 2021年。
5、海南省生理科学学会青年教师教学大赛二等奖,2021年。
6、海南医学院“教师课堂设计大赛”教学大赛比赛三等奖,院级,2022年。
7、指导学生参加第七届中国生理学知识竞赛二等奖,2022年。
8、第四届全国高校教师教学创新大赛二等奖,校级,2024年。
9、指导学生参加第九届中国生理学知识竞赛二等奖, 2024年。
(四)教学与科研成果
1、主持的项目
1、国家自然科学基金(青年项目):PDE10A/cAMP/PKA负反馈环对加压素神经元活动在大鼠脑缺血/再灌注损伤的机制研究,李冬洋,2025年1月-2027年12月
2、海南省自然科学基金项目(青年基金):催产素神经元通过Cox-2-PKA-HCN3通路改善脑卒中所致脑损伤,李冬洋/董战玲,张彩彩,焦瀚仪,2021年9日至2024年6日
2、代表性论文/专著、参编教材等
(1) Dongyang Lia, Xiao Yu Liua, Tianming Liu, Haitao Liu, Li Tong, Shuwei Jia, Yu-Feng Wang*. Neurochemical regulation of the expression and function of glial fibrillary acidic protein in astrocytes. Glia. 2019 Oct 18. PubMed PMID: 31626364.
(2) Dongyang Li, Haitao Liu, Xiaoyu Liu, Hongyang Wang, Tong Li, Xiaoran Wang, Shuwei Jia, Ping Wang, Yu-Feng Wang*. Involvement of hyperpolarization-activated cyclic nucleotide-gated channel 3 in oxytocin neuronal activity in lactating rats with pup-deprivation. ASN Neuro, 12:1759091420944658. doi:10.1177/1759091420944658
(3) Dongyang Li, Tong Li, Jiawei Yu, Xiaoyu Liu, Shuwei Jia, Xiaoran Wang, Ping Wang, Yu-Feng Wang*. Astrocytic modulation of supraoptic oxytocin neuronal activity in rat dams with pup-deprivation at different stages of lactation. Neurochemical Research. 2020 Sep 15. doi: 10.1007/s11064-020-03129-5.
(4) Dongyang Li, Xiaoyu Liu, Haitao Liu, Tong Li, Shuwei Jia, Xiaoran Wang, Ping Wang, Danian Qin, and Yu-Feng Wang*. Key roles of cyclooxygenase 2-protein kinase A-HCN3 pathway in the regulation of oxytocin neuronal activity in lactating rats with intermittent pup-deprivation. Neuroscience. 2020; 452:13-25.
(5) Dongyang Li*, Dan Cui, Shuwei Jia, Xiaoyu Liu, Xiaoran Wang, Delai Qiu and Yu-Feng Wang1*. Involvement of Supraoptic Astrocytes in Basilar Artery Occlusion-Evoked Differential Activation of Vasopressin Neurons and Vasopressin Secretion in Rats. Neurochemical Research. 2021 Feb 2. doi: 10.1007/s11064-021-03246-9
(6)Dongyang Li, Xiaoyu Liu, Tong Li, Xiaoran Wang, Shuwei Jia, Ping Wang, Yu-Feng Wang*. Involvement of protein kinase A in oxytocin neuronal activity in rat dams with pup deprivation. Neurochemical Research. 2021;46(4):980-991.
(7) Xiao Yu Liua, Dongyang Lia, Tong Li, Haitao Liu,Dan Cui, Yang Liu, Shuwei Jia, Runsheng Jiao, Hui Zhu, Fengmin Zhang, Danian Qin, Yu-Feng Wang*. Effects of intranasal oxytocin on baby deprivation-evoked aberrant maternal behavior and hypogalactia in rat dams and the underlying mechanism. Frontiers in Neuroscience, 2019,13: 122.
(8) Dongyang Li, Haitao Liu, Hongyang Wang, Shuwei Jia, Xiaoran Wang, Shuo Ling, Guichuan Chen, Xiaoyu Liu, Yu-Feng Wang*. Astrocytic Hydrogen Sulfide Regulates Supraoptic Cellular Activity in the Adaptive Response of Lactating Rats to Chronic Social Stress. ASN Neuro. 2021;13.
(9) Dan Cui, Shuwei Jia, Jiawei Yu, Dongyang Li, Tong Li, Yang Liu, Jinlong Chang, Xiaoran Wang, Xiaoyu Liu, Yu-Feng Wang. Alleviation of Cerebral Infarction of Rats With Middle Cerebral Artery Occlusion by Inhibition of Aquaporin 4 in the Supraoptic Nucleus. ASN Neuro, 2020;12:1759091420960550
(10)Ping Wang, Stephani C. Wang, Dongyang Li, Tong Li, Hai-Peng Yang, Liwei Wang, Vladimir Parpura ,and Yu-Feng Wang*. Role of Connexin 36 in Autoregulation of Oxytocin Neuronal Activity in Rat Supraoptic Nucleus. ASN Neuro, 2019,11:1-14.
(11)XiaoYu Liua, Dan Cuia, Dongyang Li, Runsheng Jiao, Xiaoran Wang, Shuwei Jia, Dan Hou, Tong Li, Haitao Liu, Ping Wang* and Yu-Feng Wang*. Oxytocin Removes Estrous Female vs. Male Preference of Virgin Male Rats: Mediation of the Supraoptic Nucleus Via Olfactory Bulbs. Front. Cell. Neurosci., 2017, 10:327
(12)Runsheng Jiaoa, Dan Cuia, Stephani C. Wang, Dongyang Li and Yu-Feng Wang*. Interactions of the Mechanosensitive Channels with Extracellular Matrix, Integrins, and Cytoskeletal Network in Osmosensation. Frontiers in Molecular Neuroscience, 2017, 10:96.
(13)Dan Cui, Shuwei Jia, Tong Li, Dongyang Li, Xiaoran Wang, Xiaoyu Liu, Yu-Feng Wang. Alleviation of brain injury by applying TGN-020 in the supraoptic nucleus via inhibiting vasopressin neurons in rats of focal ischemic stroke. Life Sci, 2020:118683
(14) Xiao-Yu Liu, Xiaoran Wang, Shuwei Jia, Tong Li, Ying Zhang, Chunmei Lu,Haixia Wen, Hongbo Jin, Hui Zhu, Danian Qin, Chunmei Hou, Yang Liu, Dongyang Li & Yu-Feng Wang. LEPPA: A teaching modality of biotechnology course for postgraduate students in biomedical majors. Innovations in Education and Teaching International. DOI: 10.1080/14703297. 2021.1997783
(15) Hongyang Wang, Yunhao Jiang, Xiaoran Wang, Haitao Liu, Dongyang Li, Shuo Ling, Shuwei Jia, Xiaoyu Liu, Yang Liu, Chunmei Hou, Yu-Feng Wang. Excitatory effects of astrocytic hydrogen sulfide on the electrical activity of oxytocin neurons in the supraoptic nucleus. Neuroendocrinology. 2022 Aug 31. doi: 10.1159/000526812
(五)学术经历及社会服务
1、工作经历
2020年10月至今,任海南医学院基础医学院与生命科学学院讲师