（一）个人基本情况

张文，男，汉族，民进会员，出生于1983年12月，湖南省醴陵市人，遗传学专业博士，研究员职称，研究领域为分子遗传学，现就职于基础医学与生命科学学院生物化学与分子生物学教研室，海南医学院分子生物学重点实验室主任。

（二）教育背景：

2001.9-2005.6   湖南农业大学生物技术专业 获理学学士学位

2005.9-2008.7   南方医科大学细胞生物学专业 获理学硕士学位

2008.9-2012.6   中国科学院昆明动物研究所遗传学专业 获理学博士学位

（三）所获荣誉

无

（四）教学与科研成果

1、主持的项目

2、代表性论文/专著、参编教材等

Xiao Li, Wen Zhang#, Todd Lencz, Ariel Darvasi, Anna Alkelai, Bernard Lerer, Hong-Yan Jiang, Deng-Feng Zhang, Li Yu, Xiu-feng Xu, Ming Li, Yong-Gang Yao. Common variants of IRF3 conferring risk of schizophrenia. Journal of Psychiatric Research 64:67-73 (2015).

Xiao Li, Wen Zhang#, Jinsong Tang, Liwen Tan, Dong Wang, Xiongjian Luo, Xiaogang Chen, Yong-Gang Yao. Do nuclear-encoded core subunits of mitochondrial complex I confer genetic susceptibility to schizophrenia in Han Chinese populations? Scientific Reports 5:11076 (2015).

Wen Zhang, Mei-Sheng Xiao, Shuang Ji, Jinsong Tang, Ling Xu, Xiao Li, Ming Li, Hui-Zhen Wang, Hong-Yan Jiang, Deng-Feng Zhang, Jicai Wang, Shuliang Zhang, Xiu-Feng Xu, Li Yu, Ping Zheng, Xiaogang Chen, Yong-Gang Yao. Promoter variant rs2301228 on the neural cell adhesion molecule 1 gene confers risk of schizophrenia in Han Chinese. Schizophrenia Research 160:88-96 (2014).

Wen Zhang, Jinsong Tang, A-Mei Zhang, Min-Sheng Peng, Hai-Bing Xie, Liwen Tan, Lin Xu, Ya-Ping Zhang, Xiaogang Chen, Yong-Gang Yao. A matrilineal genetic legacy from the Last Glacial Maximum confers susceptibility to schizophrenia in Han Chinese. Journal of Genetics and Genomics 41:397-407 (2014).

Xiao Li, Wen Zhang*, Chen Zhang, Wei Gong, Jinsong Tang, Zhenghui Yi, Dong Wang, Weihong Lu, Yiru Fang, Xiaogang Chen, Yong-Gang Yao. No association between genetic variants of the LRRK2 gene and schizophrenia in Han Chinese. Neuroscience Letters 566:210-215 (2014).

Wen Zhang, Xiaogang Chen, Wei Gong, Jinsong Tang, Liwen Tan, Hao Guo, Yong-Gang Yao. Common promoter variants of the NDUFV2 gene do not confer susceptibility to schizophrenia in Han Chinese. Behavioral and Brain Functions 6:75 (2010).

Wen Zhang, Wang-Wei Cai, Wei-Ping Zhou, Hai-Peng Li, Liang Li, Wei Yan, Qin-Kai Deng, Ya-Ping Zhang, Yun-Xin Fu, Xiang-Min Xu. Evidence of gene conversion in the evolutionary process of the codon 41/42 (-CTTT) mutation causing β-thalassemia in Southern China. Journal of Molecular Evolution 66:436-445 (2008).

学术经历及社会服务

1、工作经历

2012.7-2014.7   中国科学院昆明动物研究所 助理研究员

2015.8-2016.1   中国科学院昆明动物研究所 助理研究员

2016.1-2016.5    海南医学院专任教师

2016.6-2018.2    海南医学院 研究员

2018.3-至今 海南医学院 研究员/分子生物学重点实验室主任

2、海外经历

2014.8-2015.1   Department of Pediatrics, Indiana University School of Medicine, Postdoctoral Research Fellow (Prof. Yang Feng-Chun’s Lab)

2015.2-2015.7   Department of Biochemistry and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Post-Doctoral Associate (Prof. Yang Feng-Chun’s Lab)

3、学术团体兼职情况

海南省遗传学会理事；中国老年学和老年医学学会抗衰老分会委员

4、期刊杂志兼职情况

无

5、其他学术经历或社会服务经历

无