(一)个人基本情况
陈旭阳,女,汉族,中共党员,出生于1993年10月,湖北省襄阳市人,病理生理学专业博士,研究领域为肿瘤表观遗传学,现就职于海南医学院基础医学与生命科学学院。
(二)教育背景
2011年9月至2015年6月,就读于中国药科大学制药工程专业,获学士学位;
2017年9月至2023年9月,就读于吉林大学病理生理学专业硕博连读,获博士学位。
(三)所获荣誉
2018年度 吉林省实验动物论文大赛 优秀奖
2020年度 吉林省科技论文演讲大赛 三等奖
(四)教学与科研成果
1、主持的项目
2、代表性论文/专著、参编教材等
1. Chen X, Li M, Wang D,et al. Histone chaperone SSRP1 is required for apoptosis inhibition and mitochondrial function in HCC via transcriptional promotion of TRAP1. Biochem Cell Biol. 2023 Apr 21. PMID: 37084412.
2. Chen X, Zhang L, Wang X, et al. Stat3 shRNA delivery with folate receptor-modified multi-functionalized graphene oxide particles for combined infrared radiation and gene therapy in hepatocellular carcinoma. Anticancer Drugs. 2023 Jul 1;34(6):715-724. PMID:36729998.
3. Li M, Wang X, Chen X,et al. GK921, a transglutaminase cancer cells by inhibiting epithelial-to-mesenchymal transition. Biochim Biophys Acta Mol Basis Dis. Published online. October 30, 2023. PMID: 38084873
4. Li M, Chen X, Wang X, et al. RSL3 enhances the antitumor effect of cisplatin on prostate cancer cells via causing glycolysis dysfunction. Biochem Pharmacol. 2021 Oct;192:114741. PMID: 34428443.
5. Li M, Song D, Chen X,et al. RSL3 triggers glioma stem cell differentiation via the Tgm2/AKT/ID1 signaling axis. Biochim Biophys Acta Mol Basis Dis. 2022 Dec 1;1868(12):166529. PMID: 36041715.
6. Wang D, Wei X, Chen X,et al. GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis. Exp. Cell Res. 2021 Aug 27;112799. PMID: :34461110.