郑丹宁(Danning Zheng)，理学博士，现任海南医科大学药学院讲师(教学科研岗)。

长期致力于离子液体材料分子的理论设计与性能预测，在离子液体催化剂开发、离子液体萃取剂开发与离子液体药物分子的理论设计与性能预测等方面成果显著。以第一或通讯作者身份发表多篇高影响力学术论文于Green Energy & Environment、Journal of CO₂ Utilization、Fuel、Chemistry and Pharmacy等，主持或参与多项国家级、省部级科研项目。

参与国家级科研项目:

(1) 国家自然科学基金委员会，面上项目，82474456，基于SIRT1/Fox01调控自噬-NLRP3炎症小体途径探讨枫蓼肠胃康抗溃疡性结肠炎的机制，2025-01-01至2028-12-31，48万元，在研，参与。

(2) 国家自然科学基金委员会, 面上项目, 21975064, 类胍盐离子液体的合成、催化二氧化碳环加成反应以及机理研究, 2020-01-01 至 2023-12-31, 66万元, 结题, 参与。

主持省部级科研项目:

(1) 海南省科学技术厅，海南省自然科学基金青年基金项目，824QN268，多活性中心离子液体催化二氧化碳转化为医药中间体的研究，2024-01至2026-12，6万元，在研，主持。

主持校级科研项目:

(2) 海南医科大学教务处,2025年海南医科大学本科生科研创新培养计划, RZ2500002216,离子液体药物分子的理论设计与活性-毒性协同优化研究,2025-06至2027-06，10万元，在研，主持。

代表性成果目录:

论文:

(1) Danning Zheng^1*; Shan Jiang¹; Shijia Qin; Beibei An^*; Lifang Gao^*; Sustainable ionic liquid design for enhanced solubility and safety of Tamoxifen: A computational exploration, Sustainable Chemistry and Pharmacy, 2025, 45: 102046.

(2) Danning Zheng^*; Shan Jiang; Peiyao Zheng; Dan Zhou; Junqiang Qiu^*; Lifang Gao^*; Molecular mechanism for the interaction of natural products with ionic liquids: Insights from MD and DFT study, Journal of Molecular Liquids, 2024, 399: 124440.

(3) Danning Zheng¹; Fang Liu¹; Tengfei Wang; Zhengkun Zhang; Hans Agren^*; Jinglai Zhang^*; Marten S. G. Ahlquist^*; Li Wang^*; Role of water in dual-ionic pyrazolium salt promoted conversion of CO₂ at atmospheric pressure and room temperature, Catalysis Science & Technology, 2023, 13(6): 1818-1829.

(4) Lifang Gao^*; Rong Chen; Haixia Li; Dan Xu; Danning Zheng^*; Time-resolved fluorescence nanoprobe of acetylcholinesterase based on ZnGeO:Mn luminescence nanorod modified with metal ions, Analytical and Bioanalytical Chemistry, 2023, 415: 7047-7055.

(5) Danning Zheng^*; Dan Xu; Junqiang Qiu; Weiyi Zhang; Haixia Li^*; Dan Zhou^*; Insight into the effect of anions on cycloaddition of CO₂ catalyzed by carboxylate anion-based ionic liquids: A theoretical study by QM and MD, Journal of Molecular Liquids, 2022, 368: 120629.

(6) Tengfei Wang¹; Danning Zheng¹; Beibei An; Yi Liu; Tiegang Ren; Hans Ågren^*; Li Wang^*; Jinglai Zhang^*; Mårten S.G. Ahlquist^*; Dual-ionic imidazolium salts to promote synthesis of cyclic carbonates at atmospheric pressure, Green Energy & Environment, 2022, 7, 1327-1339.

(7) Tengfei Wang¹; Danning Zheng¹; Zhengkun Zhang; Li Wang^*; Jinglai Zhang^*; Exploration of catalytic species for highly efficient preparation of quinazoline-2,4(1H,3H)-diones by succinimide-based ionic liquids under atmospheric pressure: Combination of experimental and theoretical study, Fuel, 2022, 319, 123628.

(8) Tengfei Wang¹; Danning Zheng¹; Yuhang Hu; Jingsheng Zhou; Yi Liu; Jinglai Zhang^*; Li Wang^*; Efficient responsive ionic liquids with multiple active centers for the transformation of CO₂ under mild conditions: Integrated experimental and theoretical study, Journal of CO₂ Utilization, 2021, 49, 101573.

(9) Danning Zheng; Pan Ning; Jiamin Jiang; Fang Liu; Li Wang^*; Jinglai Zhang^*. Effect of ionic liquids clusters microenvironment on cycloaddition reaction of carbon dioxide. Journal of Molecular Liquids, 2019, 284, 68-74.

(10) Danning Zheng; Li Wang^*; Jiamin Jiang; Fang Liu; Jinglai Zhang^*. Effect of cluster of protic pyrazolium ionic liquids or epoxides on the cycloaddition of CO₂. Journal of Molecular Liquids, 2019, 295, 111652.

(11) Danning Zheng; Jingshun Zhang; Xinrui Zhu; Tiegang Ren^*; Li Wang^*; Jinglai Zhang^*. Solvent effects on the coupling reaction of CO₂ with PO catalyzed by hydroxyl imidazolium ionic liquid: Comparison of different models. Journal of CO₂ Utilization, 2018, 27, 99-106.

(12) Danning Zheng; Tengfei Wang; Xinrui Zhu; Ci Chen; Tiegang Ren; Li Wang^*; Jinglai Zhang^*. Protic pyrazolium ionic liquids for efficient chemical fixation of CO₂: design, synthesis, and catalysis. Molecular Systems Design & Engineering, 2018, 3, 348-356.

专利:

高丽芳; 郑丹宁; 李海霞; 徐丹; 陈凯 ; 一种基于金属离子修饰ZnGeO : Mn纳米棒的时间分辨荧光探针及其应用, 2024-02-13, 中国, CN202310552466.1.

邱军强; 郑丹宁; 苗晶囡; 李海霞; 胡益鸣; 一种槐棘蜂蜜椰汁茶及其制作方法,2022.12.13,中国,CN202211103170.3.

个人邮箱:hy0207126@muhn.edu.cn

个人主页:

https://www.researchgate.net/profile/Danning-Zheng-2/publications

25大学生科创项目所带学生信息