个人简介   

  潘涛，男，中共党员，博士研究生，生物医学信息与工程学院计算表观遗传学教研室, 三级教学秘书，热带生物医学信息学校级A类重点学科学科秘书。研究方向围绕生命健康问题的复杂疾病生物信息学研究，目前主持2项校级科研项目，参与发表SCI论文17篇。

教育经历：

1.2021-11至今，海南医学院，生物医学信息与工程学院，博士研究生；

2.2015-9至2018-6, 哈尔滨医科大学, 生物医学工程, 硕士研究生；

3.2010-9至2015-6，哈尔滨医科大学，生物信息学，本科。

科研与学术工作经历：

4.2021-4至今, 海南医学院, 生物医学信息与工程学院；

5.2018-8至2020-8, 清华控股有限公司；

6.2010-9至2018-6，哈尔滨医科大学。

主持及参与科研项目情况：

1.基础医学院省级重点实验室开放课题基金项目，恶性肿瘤驱动基因优选及功能分析（JCKF2021003），2021-11至2023-12，在研，项目负责人；

2.海南省重点研发计划项目，基于单细胞测序解析热带病调控因子关键技术研究与应用（ZDYF2021SHFZ051），2021-9至2023-9，在研，项目参与人；

3.海南医学院国家级自然科学研究项目培育基金重点项目，重大疾病单细胞测序关键技术研究与应用（JBGS202103），2021-10至2024-10，在研，项目参与人；

4.国家卫生健康委员会热带病防治重点实验室开放课题，融合多组学数据优选新冠感染关键RBP分子标记（2022NHCTDCKFKT31001），2021-12至2023-12，在研，项目参与人；

参与发表论文列表：

1.Jiwei Zhang#, Tao Pan#, Weiwei Zhou#, Ya Zhang, Gang Xu, Qi Xu, Si Li, Yueying Gao, Zhengtao Wang*, Juan Xu*, Yongsheng Li*. Long noncoding RNA LINC01132 enhances immunosuppression and therapy resistance via NRF1/DPP4 axis in hepatocellular carcinoma. J Exp Clin Cancer Res. 2022. (并列第一作者，SCI影响因子12.658)

2.Yongsheng Li#, Sicong Xu#, Dahua Xu#, Tao Pan, Jing Guo, Shuo Gu, Qiuyu Lin, Xia Li*, Kongning Li*, Wei Xiang*. Pediatric Pan-Central Nervous System Tumor Methylome Analyses Reveal Immune-Related LncRNAs. Front Immunol, 2022. (参与作者，SCI影响因子8.786)

3.Gang Xu#, Yueying Gao#, Tao Pan#, Si Li, Ya Zhang, Jing Guo, Zhanyu Tian, Juan Xu*, Yongsheng Li*, Xia Li*. Dynamic immune ecosystem of dengue infection revealed by single-cell sequencing. Journal of Leukocyte Biology. 2022. (并列第一作者，SCI影响因子6.011)

4.Tao Pan#, Yueying Gao#, Gang Xu#, Ping Zhou#, Si Li, Jing Guo, Haozhe Zou, Qi Xu, Xiaoyan Huang*, Juan Xu*, Yongsheng Li*. Pan-cancer analyses reveal the genetic and pharmacogenomic landscape of transient receptor potential channels. NPJ Genome Medicine, 2022. (第一作者，SCI影响因子8.617)

5.Yongsheng Li#, Sicong Xu#, Dahua Xu#, Tao Pan, Jing Guo, Shuo Gu, Qiuyu Lin, Xia Li*, Kongning Li*, Wei Xiang*. Pediatric pan-central nervous system tumors methylomes analyses reveal immune-related lncRNAs. Frontiers in Immunology, 2022. (SCI影响因子8.786)

6.Yongsheng Li#, Yunpeng Zhang#, Tao Pan#, Ping Zhou#, Weiwei Zhou, Yueying Gao, Shaojiang Zheng*, Juan Xu*. Shedding light on the hidden human proteome expands immunopeptidome in cancer. Briefings in Bioinformatics, 2022. (SCI影响因子13.994)

7.Si Li#, Weiwei Zhou#, Donghao Li#, Tao Pan, Jing Guo, Haozhe Zou, Zhanyu Tian, Kongning Li, Juan Xu*, Xia Li*, Yongsheng Li*. Comprehensive characterization of human–virus protein-protein interactions reveals disease comorbidities and potential antiviral drugs. Computational and Structural Biotechnology Journal, 2022. (SCI影响因子7.271)

8.Lingli Li#, Hongyan Yi#, Zheng Liu#, Ping Long, Tao Pan, Yuanhua Huang, Yongsheng Li*, Qi Li*, Yanlin Ma*. Genetic correction of concurrent α- and β-thalassemia patient-derived pluripotent stem cells by the CRISPR-Cas9 technology. Stem Cell Res Ther, 2022. (SCI影响因子8.079)

9.Haozhe Zou#, Tao Pan#, Yueying Gao#, Renwei Chen, Si Li, Jing Guo, Zhanyu Tian, Gang Xu, Juan Xu*, Yanlin Ma*, Yongsheng Li*. Pan-cancer assessment of mutational landscape in intrinsically disordered hotspots reveals potential driver genes. Nucleic Acids Research, 2022 Jan 21. (并列第一作者，SCI影响因子19.16)

10.Junyi Li#, Tao Pan#, Liuxin Chen#, Qi Wang, Zhenghong Chang, Weiwei Zhou, Xinhui Li, Gang Xu, Xia Li*, Yongsheng Li*, Yunpeng Zhang*. Alternative splicing perturbation landscape identifies RNA binding proteins as potential therapeutic targets in cancer. Molecular Therapy: Nucleic Acids, 2021 Apr 9. (并列第一作者，SCI影响因子8.886)

11.Tiantongfei Jiang#, Weiwei Zhou#, Zhenghong Chang#, Haozhe Zou, Jing Bai, Qisen Sun, Tao Pan, Juan Xu*, Yongsheng Li* and Xia Li*. ImmReg: The regulon atlas of immune-related pathways across cancer types. Nucleic Acids Research, 2021. (SCI影响因子19.16)

12.Yongsheng Li#, Yunpeng Zhang#, Tao Pan#, Ping Zhou#, Weiwei Zhou, Yueying Gao, Shaojiang Zheng*, Juan Xu*. Shedding light on the hidden human proteome expands immunopeptidome in cancer. Briefings in Bioinformatics, 2022 Feb 21. (并列第一作者，SCI影响因子13.994)

13.Jianping Lu#, Juan Xu#, Junyi Li#, Tao Pan#, Jing Bai, Liqiang Wang, Xiyun Jin, Xiaoyu Lin, Yunpeng Zhang, Yongsheng Li, Nidhi Sahni, Xia Li. FACER: Comprehensive Molecular and Functional Characterization of Epigenetic Chromatin Regulators. Nucleic Acids Research, 2018 Nov 2. (并列第一作者，SCI影响因子19.16)

14.Yongsheng Li#, Caiqin Huo#, Tao Pan#, Lili Li, Xiyun Jin, Xiaoyu Lin, Juan Chen, Jinwen Zhang, Zheng Guo*, Juan Xu*, Xia Li*. Systematic review regulatory principles of non-coding RNAs in cardiovascular diseases. Briefings in Bioinformatics, 2019 Jan 18. (并列第一作者, SCI影响因子13.994)

15.Tiantongfei Jiang#, Weiwei Zhou#, Zhenghong Chang#, Haozhe Zou, Jing Bai, Qisen Sun, Tao Pan, Juan Xu*, Yongsheng Li*, Xia Li*. ImmReg: the regulon atlas of immune-related pathways across cancer types. Nucleic Acids Research, 2021 Dec 2. (SCI影响因子19.16)

16.Yongsheng Li#, Lili Li#, Zishan Wang#, Tao Pan, Sahni Nidhi, Xiyun Jin, Guangjuan Wang, Junyi Li, Yunpeng Zhang*, Juan Xu*, Song Yi*, Xia Li*. LncMAP: Pan-cancer atlas of long noncoding RNA-mediated transcriptional network perturbations. Nucleic Acids Research, 2018 Feb 16. (SCI影响因子19.16)

17.Juan Xu#, Yongsheng Li#, Jianping Lu#, Tao Pan, Na Ding, Zishan Wang, Tingting Shao, Jinwen Zhang, Lihua Wang*, Xia Li*. The mRNA related ceRNA–ceRNA landscape and significance across 20 major cancer types. Nucleic Acids Research, 2015 Sep 30. (SCI影响因子19.16)

#共同第一作者，*通讯作者。