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罗卓辉

 导师简介

                                                                                                   

一、个人信息:

罗卓辉,博士,副研究员士生导师

二、教育经历

2015.09-2020.06 广州中医药大学中药学,医学博士(硕博连读

三、主要工作经历:

2020.12-2022.11 康芝药业股份有限公司/北京大学医学部,博士后

2022.12-至今          海南医科大学

四、研究方向:

    炎症与代谢性疾病药理研究。

五、主要学术成果:

主持国家自然科学基金地区科学基金项目1项海南省自然科学基金高层次人才项目1项中国博士后科学基金面上项目1项海南省博士后科研资助项目1项

代表性论文(#:第一作者*:通讯作者):

1. KY Wang, HY Hu, ZB Xu, Y Chen, Y Qiu YJ Hu, JW Huang*, ZH Luo*. 7-Methoxyflavanone Alleviates LPS-Induced Acute Lung Injury by Suppressing TLR4/NF-κB p65 and ROS/Txnip/NLRP3 Signaling. Biology. 2025, 14, 1170.

2. ZH Luo#, ZB Xu, KY Wang, HY Hu, JW Huang. Citri Sarcodactylis Fructus Alleviates LPS-Induced Acute Lung Injury by Inhibiting Inflammation and Inflammasome Activation. Food Science & Nutrition. 2025, 13: e70881.

3. JW Huang, KL Zhou, JY Li, ZB Xu, XQ Wu, TT Chen, DN Wang, HF Pan, SQ Huang*, TW Liu*, ZH Luo*, Y Gao*. Poncirin ameliorates alcoholic liver injury by regulating lipid metabolism and inflammatory response in a PPARα dependent manner. Phytomedicine. 2025, 140: 156598.

4. QQMeng, ZP Li, XF He, YH Hu, GY Wu, JW Huang, ZH Luo*, YJ Hu*, XL Shen*. Anti-TNBC effects of Lappaol F by targeting epithelial-mesenchymal transition via regulation of GSK-3β-YAP-β-catenin and PI3K-AKT pathways. Front Pharmacol. 2025, 16:1496511.

5. ZB Xu, KY Wang, HY Hu, YJ Hu*, JW Huang,*, ZH Luo*. Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience. International Immunopharmacology. 2025, 148, 114101.

6. ZB Xu, HY Hu, KY Wang, ZY Zhou, XQ He, XA Huang, YJ Hu*, JW Huang*, ZH Luo*. Sinensetin, a polymethoxyflavone from citrus fruits, ameliorates LPS-induced acute lung injury by suppressing Txnip/NLRP3/Caspase-1/GSDMD signaling-mediated inflammatory responses and pyroptosis. Food Funct. 2024, 15(14): 7592-7604.

7. ZB Xu, JY Li, KL Zhou, KY Wang, HY Hu, YJ Hu*, Y Gao*, ZH Luo*, JW Huang*. Exocarpium Citri Grandis ameliorates LPS-induced acute lung injury by suppressing inflammation, NLRP3 inflammasome, and ferroptosis. J Ethnopharmacol. 2024, 329: 118162.

8. JW Huang, ZB Xu, JY Li, XQ He, XA Huang, XL Shen*, ZH Luo*. Systems pharmacology-based dissection of potential mechanisms of Exocarpium Citri Grandis for the treatment of chronic bronchitis. Arab J Chem. 2024. 17(1): 105428.

六、联系方式:

    zhuohuiluo@muhn.edu.cn