个人简介
江一舟,博士、副研究员、硕士研究生导师。中国共产主义青年团第十九次全国代表大会代表、中国青年科技工作者协会第七次会员代表大会代表、海南省高层次人才、海南省人才团队核心成员、海南医科大学拔尖人才。现任中国青年科技工作者协会会员、海南省青年科技工作者协会会员、中国民族医药学会方药量效研究分会常务理事。主要从事衰老生物学研究。获得2019年粤港澳大湾区高价值专利培育布局大赛五十强等奖项。
教育背景
2017-2022 澳门大学&南方科技大学, 博士
2013-2017 南方科技大学,学士
工作经历
2022.09-2022.12 北京大学
2022.12至今 海南医科大学(海南省医学科学院), 副研究员
研究方向
衰老机制解析与干预策略开发
期刊论文
1.Jiang Y, Gaur U, Cao Z, Hou S# & Zheng W#. Dopamine D1- and D2-like receptors oppositely regulate lifespan via a dietary restriction mechanism in Caenorhabditis elegans. BMC Biology 20, 71 (2022).
2.Jiang Y*, Yan F*, Feng Z, Lazarovici P & Zheng W. Signaling Network of Forkhead Family of Transcription Factors (FOXO) in Dietary Restriction. Cells 9 (2020).
3.Jiang Y*, Rubin L*, Zhou Z, Zhang H, Su Q, Hou S, Lazarovici P & Zheng W. Pharmacological therapies and drug development targeting SARS-CoV-2 infection. Cytokine & Growth Factor Reviews (2022).
4.Jiang Y, Gaur U, Cao Z, Hou S# & Zheng W#. Quetiapine shortens the lifespan of Caenorhabditis elegans through DOP-2, DAF-2 and RSKS-1. International Journal of Molecular Sciences 23(21), 12927 (2022).
5.Jiang Y*, Rubin L*, Peng T, Liu L, Xing X, Lazarovici P & Zheng W. Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapy. International Journal of Biological Sciences 18, 459-472 (2022).
6.Jiang Y*, Peng T*, Gaur U, Silva M, Little P, Chen Z, Qiu W#, Zhang Y# & Zheng W#. Role of Corticotropin Releasing Factor in the Neuroimmune Mechanisms of Depression: Examination of Current Pharmaceutical and Herbal Therapies. Frontiers in Cellular Neuroscience 13, 290 (2019).
7.Peng T*, Jiang Y*, Farhan M, Lazarovici P, Chen L & Zheng W. Anti-inflammatory Effects of Traditional Chinese Medicines on Preclinical in vivo Models of Brain Ischemia-Reperfusion-Injury: Prospects for Neuroprotective Drug Discovery and Therapy. Frontiers in Pharmacology 10, 204 (2019).
8.Li S, Jiang Y, Xing X, Lin R, Li Q, Zhou W, Qiu W & Zheng W. Protective Mechanism of Berberine on Human Retinal Pigment Epithelial Cells against Apoptosis Induced by Hydrogen Peroxide via the Stimulation of Autophagy. Oxidative Medicine and Cellular Longevity 2021 (2021).
9.Zhao X*, Liu L*, Jiang Y, Silva M, Zhen X & Zheng W. Protective Effect of Metformin against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial (RPE) Cells by Enhancing Autophagy through Activation of AMPK Pathway. Oxidative Medicine and Cellular Longevity 2020, 2524174 (2020).
10.Zhao X, Huang X, Yang C, Jiang Y, Zhou W & Zheng W. Artemisinin attenuates amyloid-induced brain inflammation and memory impairments by modulating TLR4/NF-κB signaling. International Journal of Molecular Sciences 23, 6354 (2022).
11.Yan F, Wang R, Li S, Zhao X, Jiang Y, Liu L, Fang J, Zhen X, Lazarovici P & Zheng W. FoxO3a suppresses neuropeptide W expression in neuronal cells and in rat hypothalamus and its implication in hypothalamic-pituitary-adrenal (HPA) axis. International Journal of Biological Sciences 16, 2775-2787 (2020).
12.Yan F, Liao R, Silva M, Li S, Jiang Y, Peng T, Lazarovici P & Zheng W. Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway. Journal of Cellular and Molecular Medicine 24, 6208-6219 (2020).
13.Cui Y, Wang K, Jiang D, Jiang Y, Shi D, DeGregori J, Waxman S & Ren R. Promoting longevity with less cancer: the 2022 International Conference on Aging and Cancer. Aging and Cancer 4:111–120 (2023).
(* 共同第一作者)
专著章节
Jiang Y & Zheng W. Cell Damage and Transformation in Aging. In: Gu D., Dupre M. (eds) Encyclopedia of Gerontology and Population Aging. Springer, Cham (2019).